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OpenUpdated 9 Jun 2026Mixed

MRC: new investigator research grant: applicant-led

Medical Research Council (MRC) · International

Grant funding to support researchers transitioning to independence to lead their own discovery research projects within the Medical Research Council (MRC) remit, advancing understanding of human health and disease and enabling early career researchers to establish independent research careers.

Summary

Deadline

Rolling

Complexity

Medium

Time to apply

20-60 hours

Updated

9 Jun 2026

Grant funding to support researchers transitioning to independence to lead their own discovery research projects within the Medical Research Council (MRC) remit, advancing understanding of human health and disease and enabling early career researchers to establish independent research careers.

Eligibility

Applicant types

Research, Public Sector

Business size

Research organisation

Industries

Biomedical research, medical sciences and health-related research fields aligned with MRC research priorities.

Match funding

Required

Requirements

Early-career researchers transitioning to independence with support from an eligible research organisation. Applicants may include postdoctoral researchers, lecturers, junior fellows or equivalent research staff who have not yet achieved research independence. The project must be hosted and submitted by an eligible UK research organisation registered on the UKRI Funding Service. Research propos...

Eligible applicants

Early-career researchers transitioning to independence with support from an eligible research organisation. Applicants may include postdoctoral researchers, lecturers, junior fellows or equivalent research staff who have not yet achieved research independence.

Funding and scope

Benefit amount

No fixed funding limit; typical full economic cost (FEC) for projects is under £1,000,000.

Total fund available

Not specified

Funding intensity

MRC funds 80% of full economic cost (FEC).

Payment type

Grant (typically 80% FEC in arrears)

Eligible scope

Research proposals must advance understanding of human health and disease and align with one of the MRC research areas including infections and immunity, molecular and cellular medicine, neurosciences and mental health, or population and systems medicine. MRC_ new investigator research …

Eligible expenses

  • Investigator salary contribution (up to 50% of working time), research staff salaries, consumables, equipment, travel costs, data management and dissemination, estates and indirect costs, and NHS research costs where relevant.

Ineligible costs

  • Costs not eligible under MRC funding opportunity and UKRI FEC terms.

Application and risks

Application platform

UKRI Funding Service

Competitiveness

Competitive Selection

Decision timeline

MRC aims to complete the full assessment process within approximately 10 months from submission. MRC_ new investigator research …

Assessment process

Applications are examined for eligibility and scope, undergo expert peer review, are shortlisted by a panel and then considered by a funding panel for final funding decisions. MRC_ new investigator research …

Application sections

  • Summary, core team details, applicant eligibility statement, research vision, research approach and methodology, reproducibility and statistical design, data management plan, career development plan, applicant and team capability, research organisation support, project partners, ethical considerations and resource justification.

Application components

Not specified

Decision risks

Applications may be rejected if they fall outside the MRC remit, fail eligibility checks, exceed submission limits, or do not demonstrate the applicant’s readiness for research independence.

Timeline and partners

Opening date

7 Apr 2026

Project duration

Typically 3 years.

Project start

Not specified

Project end

Not specified

Co-funders

  • None specified

Collaboration rules

  • Collaborative teams are permitted. Project co-leads, specialists and technical staff may be included where they provide essential complementary expertise to the project.
  • International project co-leads and collaborators are allowed where they provide significant intellectual contribution to the project.

Consortium requirements

  • Not mandatory. Projects may be led by a single investigator with optional collaborators or co-leads where necessary.

Additional guidance

[{"label":"Research Category","value":"Discovery research and fundamental biomedical research within the MRC remit."},{"label":"Subcontractors","value":"Subcontracting is allowed where required for specific elements of the research project and must be justified in the application budget."},{"label":"Interview Stage","value":"Not specified"},{"label":"Key Requirements","value":"Applicants must demonstrate readiness to transition to independence, lead the project intellectually, and provide a strong research proposal aligned with MRC research priorities and supported by their host organisation."},{"label":"Renewal Rules","value":"New investigator research grants are not renewable. MRC_ new investigator research …"},{"label":"Important Notes","value":"Applicants are limited to two submissions as project lead across MRC applicant-led funding opportunities within a rolling 12-month period. Resubmission of unsuccessful applications is normally only allowed after a 12-month waiting period unless early resubmission is permitted"}]

Quick facts

Status
Open
Deadline
Rolling
Funding amount
No fixed funding limit; typical full economic cost (FEC) for projects is under £1,000,000.
Funding band
Mid (£500k-£5M)
Funding type
Grant
Payment type
Grant (typically 80% FEC in arrears)
Audience
Research Innovation, Public Sector, Mixed
Industry
Biomedical research, medical sciences and health-related research fields aligned with MRC research priorities.
Last updated
9 Jun 2026
Published
26 Nov 2025